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  • 4 out of 5
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  • Instructed by: Hansom Rob
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Course Description

Because cells are divided in many parts that serve different functions some cellular goodies need to be transported from one part of the cell to another for it to function smoothly. There is an entire class of proteins called ‘molecular motors’, such as myosin 5, that specialize in transporting cargo using chemical energy as fuel.

Remarkably, these proteins not only function like nano-scale lorries, they also look like a two-legged creature that takes very small steps. But exactly how Myosin 5 did this was unclear.

The motion of myosin 5 has now been recorded by a team led by Oxford University scientists using a new microscopy technique that can ‘see’ tiny steps of tens of nanometres captured at up to 1000 frames per second. The findings are of interest for anyone trying to understand the basis of cellular function but could also help efforts aimed at designing efficient nanomachines.

Until now, we believed that the sort of movements or steps these proteins made were random and free-flowing because none of the experiments suggested otherwise,’ said Philipp Kukura of Oxford University’s Department of Chemistry who led the research recently reported in the journal eLife. ‘However, what we have shown is that the movements only appeared random; if you have the capability to watch the motion with sufficient speed and precision, a rigid walking pattern emerges.’

Because cells are divided in many parts that serve different functions some cellular goodies need to be transported from one part of the cell to another for it to function smoothly. There is an entire class of proteins called ‘molecular motors’, such as myosin 5, that specialise in transporting cargo using chemical energy as fuel.

Curriculum

Section 1: Preparing the local tools
Because cells are divided in many parts that serve different functions some cellular goodies need to be transported from one part of the cell to another for it to function smoothly. There is an entire class of proteins called ‘molecular motors’, such as myosin 5, that specialize in transporting cargo using chemical energy as fuel.
Because cells are divided in many parts that serve different functions some cellular goodies need to be transported from one part of the cell to another for it to function smoothly. There is an entire class of proteins called ‘molecular motors’, such as myosin 5, that specialize in transporting cargo using chemical energy as fuel.
Because cells are divided in many parts that serve different functions some cellular goodies need to be transported from one part of the cell to another for it to function smoothly. There is an entire class of proteins called ‘molecular motors’, such as myosin 5, that specialize in transporting cargo using chemical energy as fuel.
Because cells are divided in many parts that serve different functions some cellular goodies need to be transported from one part of the cell to another for it to function smoothly. There is an entire class of proteins called ‘molecular motors’, such as myosin 5, that specialize in transporting cargo using chemical energy as fuel.
Because cells are divided in many parts that serve different functions some cellular goodies need to be transported from one part of the cell to another for it to function smoothly. There is an entire class of proteins called ‘molecular motors’, such as myosin 5, that specialize in transporting cargo using chemical energy as fuel.

About Instructor Hansom Rob

The figure that now stood by its bows was tall and swart, with one white tooth evilly protruding from its steel-like lips. Here, it must needs be said, that accidents like this have in more than one case occurred to ships in violent storms. The magnetic energy, as developed in the mariner's needle, is, as…

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  1. The Student WP Theme
    Rated 4 out of 5

    Oxford University scientists using a new microscopy technique that can ‘see’ tiny steps of tens of nanometres

  2. The Student WP Theme
    Rated 4 out of 5

    There is an entire class of proteins called ‘molecular motors’, such as myosin 5, that specialize in transporting cargo using chemical energy as fuel.

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